Jae户珥

Jae户珥

Associate Professor of 生物学

F.W. Olin Science Center, Room 2340
1250 N. 达特茅斯大街.
Claremont, CA 91711
909.607.4039
jae_hur@dektinary.com

Education and Professional Experience

  • B.A., 生物学, California Institute of Technology
  • PhD, 生物学, Harvard University
  • Postdoctoral 研究 Fellow, Harvard University
  • Postdoctoral 研究 Fellow, University of California Los Angeles
  • 访问ing Assistant Professor of 生物学, Harvey Mudd College

教学

  • Bio 52: Introduction to 生物学
  • Core Lab 57: Synthetic 生物学
  • Bio 111: 分子生物学 Lab
  • Bio 186: 分子生物学 of Aging Seminar

研究兴趣

Aging is the greatest risk factor for almost all leading causes of death and disease in developed countries, yet relatively little is known about the basic molecular mechanisms that belie the aging process. Our aims are to elucidate the fundamental genetic and physiological pathways that govern organismal lifespan. 具体地说, we are focused on using powerful genetic, 分子生物学, and biochemical tools available for 黑腹果蝇 research to discover novel pathways that affect longevity and to tease apart both the upstream causes and downstream effects of known interventions that alter longevity.

出版物

  • 布什 EC, 阿道夫 SC, Donaldson-Matasci MC, 户珥JH, and Schulz D (2021) Incorporating Programming, Modeling and Data Analysis into an Introductory 生物学 Course. Journal of College Science 教学 50:14-18.
  • Nguyen NN, Rana A, Goldman C, Moore R, Tai J, Hong Y, Shen J, Walker DW, 户珥JH (2019) Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in 黑腹果蝇. Sci代表 9(1):3170.
  • Signorovitch, 户珥J, Gladyshev E, Meselson M (2016) Evidence for meiotic sex in bdelloid rotifers. 咕咕叫杂志 26:R754-R755.
  • Signorovitch, 户珥J, Gladyshev E, Meselson M (2015) Allele Sharing and Evidence for Sexuality in a Mitochondrial Clade of Bdelloid Rotifers. 遗传学 200(2):581-590.
  • 户珥JH, Stork DA, Walker DW (2014) Complex-I-ty in aging. J生物能源 46:329-335.
  • 户珥JH, Bahadorani年代, Graniel J, 克勒CL, Ulgherait米, Rera米, 琼斯DL, Walker DW (2013) Increased longevity mediated by yeast NDI1 expression in Drosophila intestinal stem and progenitor cells. 老化(奥尔巴尼) 5:662-681.
  • 曹J, 户珥JH, Graniel J, 奔驰S, Walker DW (2012) Expression of yeast NDI1 rescues a Drosophila complex I assembly defect. 《太阳2注册平台》 7:e50644.
  • Rera米, Bahadorani年代, 曹J, 克勒CL, Ulgherait米, 户珥JH, 安萨里WS, 小罗涛, 琼斯DL, Walker DW (2011) Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. 细胞金属底座 14:623-634.
  • 曹J, 户珥JH, Walker DW (2011) The role of mitochondria in Drosophila aging. Exp Gerontol 46:331-334.
  • 户珥JH, 曹J, Walker DW (2010) Aging: Dial M for Mitochondria. 老化(奥尔巴尼) 2:69-73.
  • Bahadorani年代, 户珥JH, 小罗涛, Vu K, Walker DW (2010) Perturbation of mitochondrial complex V alters the response to dietary restriction in Drosophila. 衰老细胞 9:100-103.
  • 户珥JH, Walker DW (2009) p53, sex, and aging: lessons from the fruit fly. 老化(奥尔巴尼) 1:881-883.
  • 柯普兰JM，赵杰，小罗涛， 户珥JH, Bahadorani年代, Arabyan T, 拉比J, Soh J, Walker DW (2009) Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain. 咕咕叫杂志 19:1591-1598.
  • Van Doninck K, 曼迪哥毫升， 户珥JH, 王P, Guglielmini J, Milinkovitch MC, 莱恩WS, Meselson M (2009) Phylogenomics of unusual histone H2A variants in bdelloid rotifers. 公共科学图书馆麝猫 5:e1000401.
  • 户珥JH, Van Doninck K, 曼迪哥毫升， Meselson M (2009) Degenerate tetraploidy was established before bdelloid rotifer families diverged. Mol生物进化 26:375-383.